{"id":958,"date":"2018-01-02T11:11:52","date_gmt":"2018-01-02T10:11:52","guid":{"rendered":"http:\/\/klubcf.sk\/?p=958"},"modified":"2018-02-18T16:48:26","modified_gmt":"2018-02-18T15:48:26","slug":"prehlad-prebiehajuceho-vyskumu-liekov","status":"publish","type":"post","link":"https:\/\/klubcf.sk\/index.php\/2018\/01\/02\/prehlad-prebiehajuceho-vyskumu-liekov\/","title":{"rendered":"Preh\u013ead prebiehajuceho v\u00fdskumu liekov vo svete pre CF"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-964 aligncenter\" src=\"http:\/\/klubcf.sk\/wp-content\/uploads\/2018\/01\/Orkambi-300x149.png\" alt=\"\" width=\"300\" height=\"149\" srcset=\"https:\/\/klubcf.sk\/wp-content\/uploads\/2018\/01\/Orkambi-300x149.png 300w, https:\/\/klubcf.sk\/wp-content\/uploads\/2018\/01\/Orkambi.png 466w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<p>Lieky, ktor\u00e9 by pacientom s CF pomohli, s\u00fa \u010diasto\u010dne na svete. Na\u0161ou snahou bude z\u00edska\u0165 ich pre n\u00e1s na Slovensko.<\/p>\n<p>Aby sme sa vedeli lep\u0161ie orientova\u0165 pon\u00fakame preh\u013ead a odkaz, kde sa d\u00e1 pr\u00eds\u0165 k \u010fal\u0161\u00edm inform\u00e1ciam.<\/p>\n<p>V\u00fdskum a v\u00fdvoj liekov s\u00fa na\u0161a n\u00e1dej.&nbsp;<\/p>\n<p>Tabu\u013eka preh\u013eadu liekov&nbsp;<b>pre opravu prote\u00ednu CFRT tu :&nbsp;<\/b>&nbsp;<a href=\"http:\/\/klubcf.sk\/wp-content\/uploads\/2018\/01\/PREHLAD-VYSKUMU-OPRAVA-CFRT-PROTEINU.pdf\">PREHLAD VYSKUMU OPRAVA CFRT PROTEINU<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>Moment\u00e1lne s\u00fa schv\u00e1len\u00e9 tieto dva lieky z preh\u013eadu<\/p>\n<p>spolo\u010dnos\u0165 Vertex Pharmaceutical&nbsp;<\/p>\n<p>n\u00e1zov lieku<strong> Ivafactor (Kalydeco)<\/strong>&nbsp;<\/p>\n<p>popis &#8211; Or\u00e1lny liek na opravu chybn\u00e9ho CFTR prote\u00ednu. Pom\u00e1ha otv\u00e1ra\u0165 chloridov\u00fd kan\u00e1l na povrchu bunky, \u010d\u00edm umo\u017en\u00ed prechod chloridov a sol\u00ed z a do bunky. Prv\u00fd liek dostupn\u00fd na trhu pod n\u00e1zvom Kalydeco&nbsp;<\/p>\n<p>Schv\u00e1len\u00e9 u\u017e pre deti od 2 rokov, pre 38 mut\u00e1ci\u00ed.&nbsp;<\/p>\n<p><strong>Liek pre\u0161iel v\u0161etk\u00fdmi potrebn\u00fdmi f\u00e1zami a je dostupn\u00fd pre pacientov.&nbsp;<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>spolo\u010dnos\u0165 Vertex Pharmaceutical&nbsp;<\/p>\n<p>n\u00e1zov lieku <strong>Lumacaftor a Ivacaftor ( Orkambi)&nbsp;<\/strong><\/p>\n<p>popis &#8211; Kombin\u00e1cia Ivafactoru, ktor\u00fd otv\u00e1ra chloridov\u00fd kan\u00e1l na povrchu bunky ako je pop\u00edsan\u00e9 na bode vy\u0161\u0161ie a Lumacaftor, ktor\u00fd m\u00e1 opravi\u0165 chybn\u00fd prote\u00edn CFRT a dopravi\u0165 ho na povrch bunky.&nbsp;<\/p>\n<p>schv\u00e1len\u00e9 na trhu od 6r. pre F508del homozygot. Dchva\u013euje sa pre vek 2-5r.&nbsp;<\/p>\n<p><strong>liek pre\u0161iel v\u0161etkymi potrebn\u00fdmi f\u00e1zami a je dostupn\u00fd pre pacientov.&nbsp;<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>Zdroj, str\u00e1nka CFF kde n\u00e1jdete odkazy u\u017e na konr\u00e9tne \u0161t\u00fadie a p\u00f4vodn\u00e9 podrobnej\u0161ie inform\u00e1cie v anglickom jazyku:<\/p>\n<p><a href=\"https:\/\/www.cff.org\/trials\/pipeline\">https:\/\/www.cff.org\/trials\/pipeline<\/a><\/p>\n<p>\u010eakujeme za spracovanie -\u0160tep-<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lieky, ktor\u00e9 by pacientom s CF pomohli, s\u00fa \u010diasto\u010dne na svete. Na\u0161ou snahou bude z\u00edska\u0165 ich pre n\u00e1s na Slovensko. Aby sme sa vedeli lep\u0161ie orientova\u0165 pon\u00fakame preh\u013ead a odkaz, kde sa d\u00e1 pr\u00eds\u0165 k \u010fal\u0161\u00edm inform\u00e1ciam. V\u00fdskum a v\u00fdvoj liekov s\u00fa na\u0161a n\u00e1dej.&nbsp; Tabu\u013eka preh\u013eadu liekov&nbsp;pre opravu prote\u00ednu CFRT tu :&nbsp;&nbsp;PREHLAD VYSKUMU OPRAVA CFRT [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1009,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[10],"tags":[],"class_list":["post-958","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-vyskum-a-vyvoj"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Preh\u013ead prebiehajuceho v\u00fdskumu liekov vo svete pre CF - klubcf.sk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/klubcf.sk\/index.php\/2018\/01\/02\/prehlad-prebiehajuceho-vyskumu-liekov\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Preh\u013ead prebiehajuceho v\u00fdskumu liekov vo svete pre CF - klubcf.sk\" \/>\n<meta property=\"og:description\" content=\"Lieky, ktor\u00e9 by pacientom s CF pomohli, s\u00fa \u010diasto\u010dne na svete. 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